In the 1900 Federal Census, Amie M. Holden is living in Manhattan, New York with her husband and daughter. Also with them is Agnes Everett, age 27, born RI, a violinist.
Apparently there was a divorce because Warren Holden, doctor, is still in Manhattan in 1920, with a younger wife named Helen.
In 1930 Amie M. Holden, widow age 50, b MA parents b RI/MA, is living at 140 Pinehurst Ave., Manhattan, NY. I think this is the same person, and that she is really divorced, not widowed.